Invitrogen

PYY Monoclonal Antibody (4)

图: 1 / 1

PYY Antibody (ABS 051-04-02) in ELISA

Sandwich ELISA of PYY using ABS 051-04 as the capture antibody and ABS 029-01B as the biotinylated detection antibody.

Product Image Gallery

产品信息

ABS 051-04-02

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

抗原

Synthetic N-terminal fragment of human PYY(3-36) coupled to carrier.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.08 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

15mM sodium azide

保存条件

4° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2536229

产品详细信息

Specificity: ABS 051-04-02 binds human PYY (3-36). This antibody does not cross-react with PYY (1-36) from mouse, rat, dog or pig samples.

Reactivity: ABS 051-04-02 binds free PYY (3-36) in solution. The recommended ELISA dilution is 1:20,000 for PYY (3-36) coated directly at 1 µg/mL. ABS 051-04-02 can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibody ABS 029-01-02.

NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

靶标信息

Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。